LFU:online

Relevant and applied aspects of pharmaceutical chemistry and technology including aspects for drug optimization, stability; drug analytics quality control including validation and GLP aspects; types of drug substances including Biologics, Advanced Therapy Medicinal Products (ATMP) and vaccines, industrial perspective

Pharmaceutical technology (Braun 9UE, Fürtinger 3UE)

• Pharmaceutical preformulation: basic concepts of solid pharmaceutical substances, their solid-state forms and their characteristics

• Design and production of dosage forms for different routes of administration including biopharmaceutical aspects

• Modified release drug delivery systems, innovative dosage forms (micro-and nanoparticles, liposomes, micelles, cyclodextrins inclusion complexes, etc.), 3D printed pharmaceuticals and Devices (Fürtinger)

• Specifications, characterization and quality control of dosage forms, pharmaceutical stability testing

Drug Design/Chemistry (Kaserer)

• Required compound properties (and surrogate descriptors such as PhysChem properties) (1UE)

• Hit finding, validation, and follow up (3UE)

• Multiparameter compound optimization (for example potency, solubility, permeability, metabolic stability, …) (8UE)

• PK/PD profiles (2UE)

• Work culture and required expertise and resources (1UE)

Analytical validation (Ganzera): 

• Validation of analytical methods in theory (i.e. meaning and relevance of individual validation parameters, their assessment and interpretation)

Biologics (Fürtinger)

ATMPs (Singewald)

Impfstoffe (Wollmann)

Radiopharmaka (Decristoforo)

Industrial perspective (Fürtinger)

• Drug Substance Production

• Pharmaceutical Technology: Formulation development, Process development

• Process implantation in commercial scale and validation (GMP)

• Quality control, release, GLP and stability

Vorlesung (Computer-unterstützte visualisierte Präsentation, online Handouts)

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